Peer-review publications
In prep
Sindhuja Tirumalai Govindarajan, Elizabeth Mamourian; Guray Erus; Ahmed Abdulkadir; Randa Melhem; Jimit Doshi; Raymond Pomponio; Duygu Tosun; Yang An; Aristeidis Sotiras; Daniel S. Marcus; Pamela J. LaMontagne; Mark A. Espeland; Colin L. Masters; Paul Maruff; Lenore J. Launer; Jurgen Fripp; Sterling C. Johnson; John C. Morris; Marilyn S. Albert; R. Nick Bryan; Mohamad Habes; Haochang Shou; David A. Wolk; Ilya M. Nasrallah, and Christos Davatzikos; Machine-learning based MRI neuro-anatomical signatures associated with cardiovascular and metabolic risk factors
Sindhuja Tirumalai Govindarajan, Elizabeth Mamourian, Guray Erus, Yuhan Cui, Randa Melhem, Haochang Shou, Christos Davatzikos; Brain anomaly detection in unspecified TBI using population neuroimaging data
Published
Sindhuja T Govindarajan, Ruiqi Pan, Leigh Charvet, Lauren Krupp, Timothy Duong: Gray matter morphometry correlates with attentional efficiency in young-adult multiple sclerosis; Brain Sciences, 01/2021, Featured cover story, https://doi.org/10.3390/brainsci11010080
Elena Herranz, Céline Louapre, Constantina Andrada Treaba, Sindhuja T Govindarajan, Russell Ouellette, Gabriel Mangeat, Marco L Loggia, Julien Cohen-Adad, Eric C Klawiter, Jacob A Sloane, Caterina Mainero: Profiles of cortical inflammation in multiple sclerosis by 11C-PBR28 MR-PET and 7 Tesla imaging; Multiple Sclerosis Journal, 10/2020; https://doi.org/10.1177/1352458519867320
Sindhuja T Govindarajan, Yilin Liu, M. Andrea Parra, Lev Bangiyev, Lauren Krupp, Leigh Charvet, Tim Q Duong: White matter correlates of slowed information processing speed in unimpaired multiple sclerosis patients with young age onset; Brain Imaging and Behavior, 08/2020; https://doi.org/10.1007/s11682-020-00345-z
David J Ouellette, Eric Van Staalduinen, Syed H Hussaini, Sindhuja T Govindarajan, Patricia Stefancin, Dan-Ling Hsu, Timothy Q Duong: Functional, anatomical and diffusion tensor MRI study of radiology expertise; PLOS ONE, 04/2020; https://doi.org/10.1371/journal.pone.0231900
Lilianne R Mujica-Parodi, Anar Amgalan, Syed Fahad Sultan, Botond Antal, Xiaofei Sun, Steven Skiena, Andrew Lithen, Noor Adra, Eva-Maria Ratai, Corey Weistuch, Sindhuja Tirumalai Govindarajan, Helmut H Strey, Ken A Dill, Steven M Stufflebeam, Richard L Veech, Kieran Clarke: Diet modulates brain network stability, a biomarker for brain aging, in young adults; Proceedings of the National Academy of Sciences, 03/2020, https://doi.org/10.1073/pnas.1913042117
Patricia Stefancin, Sindhuja T Govindarajan, Lauren Krupp, Leigh Charvet, Timothy Q Duong; Resting-State Functional Connectivity Networks Associated with Fatigue in Multiple Sclerosis with Early Age Onset; Multiple Sclerosis and Related Disorders, 03/2019; https://doi.org/10.1016/j.msard.2019.03.020
M. Andrea Parra Corral, Sindhuja T.Govindarajan, Patricia Stefancin, Lev Bangiyev, Patricia K.Coyle, Tim Q.Duong; Characterization of gray-matter multiple sclerosis lesions using double inversion recovery, diffusion, contrast-enhanced, and volumetric MRI; Multiple Sclerosis and Related Disorders, 03/2019; https://doi.org/10.1016/j.msard.2019.03.021
Céline Louapre, Sindhuja T Govindarajan, Costanza Giannì, Nancy Madigan, Jacob A Sloane, Constantina A Treaba, Elena Herranz, Revere P Kinkel, Caterina Mainero. Heterogeneous pathological processes account for thalamic degeneration in multiple sclerosis: insights from 7 T imaging. Multiple Sclerosis Journal; 2018/10; https://doi.org/10.1177%2F1352458517726382
Céline Louapre, Sindhuja T. Govindarajan, Costanza Giannì, Nancy Madigan, A. Scott Nielsen, Jacob A. Sloane, Revere P. Kinkel, Caterina Mainero: The association between intra- and juxta-cortical pathology and cognitive impairment in multiple sclerosis by quantitative T2* mapping at 7T MRI. NeuroImage: Clinical 11/2016; 12(C)., https://doi.org/10.1016/j.nicl.2016.11.001
Elena Herranz, Costanza Giannì, Céline Louapre, Constantina A Treaba, Sindhuja T Govindarajan, Russell Ouellette, Marco L Loggia, Jacob A Sloane, Nancy Madigan, David Izquierdo-Garcia, Noreen Ward, Gabriel Mangeat, Tobias Granberg, Eric C Klawiter, Ciprian Catana, Jacob M Hooker, Norman Taylor, Carolina Ionete, Revere P Kinkel, Caterina Mainero: The neuroinflammatory component of gray matter pathology in multiple sclerosis. Annals of Neurology 09/2016; 80(5)., https://doi.org/10.1002/ana.24791
Céline Louapre, Govindarajan ST, Costanza Giannì, Christian Langkammer, Jacob A Sloane, Kinkel RP, Caterina Mainero: Beyond focal cortical lesions in MS: An in vivo quantitative and spatial imaging study at 7T. Neurology 10/2015; 85(19)., https://doi.org/10.1212/WNL.0000000000002106
Céline Louapre, Sindhuja T Govindarajan, Costanza Giannì, Julien Cohen-Adad, Michael D Gregory, A Scott Nielsen, Nancy Madigan, Jacob A Sloane, Revere P Kinkel, Caterina Mainero: Is the Relationship between Cortical and White Matter Pathologic Changes in Multiple Sclerosis Spatially Specific? A Multimodal 7-T and 3-T MR Imaging Study with Surface and Tract-based Analysis. Radiology 09/2015; 278(2):150486., https://doi.org/10.1148/radiol.2015150486
G Mangeat, S.T. Govindarajan, C Mainero, J Cohen-Adad: Multivariate combination of magnetization transfer, T2* and B0 orientation to study the myelo-architecture of the in vivo human cortex. NeuroImage 06/2015; 119., https://doi.org/10.1016/j.neuroimage.2015.06.033
Caterina Mainero, Céline Louapre, Sindhuja T Govindarajan, Costanza Giannì, A Scott Nielsen, Julien Cohen-Adad, Jacob Sloane, Revere P Kinkel: A gradient in cortical pathology in multiple sclerosis by in vivo quantitative 7 T imaging. Brain 02/2015; 138(4)., https://doi.org/10.1093/brain/awv011
Sindhuja T Govindarajan, Julien Cohen‐Adad, Maria Pia Sormani, Audrey P Fan, Céline Louapre, Caterina Mainero: Reproducibility of T2* mapping in the human cerebral cortex in vivo at 7 tesla MRI. Journal of Magnetic Resonance Imaging 11/2014; 42(2)., https://doi.org/10.1002/jmri.24789
Audrey P Fan, Sindhuja T Govindarajan, R Philip Kinkel, Nancy K Madigan, A Scott Nielsen, Thomas Benner, Emanuele Tinelli, Bruce R Rosen, Elfar Adalsteinsson, Caterina Mainero: Quantitative oxygen extraction fraction from 7-Tesla MRI phase: Reproducibility and application in multiple sclerosis. Journal of Cerebral Blood Flow & Metabolism 10/2014; 35(1)., https://doi.org/10.1038/jcbfm.2014.187
Walter G. O'Dell, Sindhuja Tirumalai Govindarajan, Ankit Salgia, Satyanarayan Hegde, Sreekala Prabhakaran, Ender A. Finol, R. James White: Traversing and labeling interconnected vascular tree structures from 3D medical images. SPIE Medical Imaging; 03/2014, https://doi.org/10.1117/12.2044140]
Dana L Helmreich, Daniel Tylee, John P Christianson, Kenneth H Kubala, Sindhuja T Govindarajan, William E O'Neill, Kyeesha Becoats, Linda Watkins, Steve F Maier: Active behavioral coping alters the behavioral but not the endocrine response to stress. Psychoneuroendocrinology 05/2012; 37(12)., https://doi.org/10.1016/j.psyneuen.2012.04.005
Conference presentations
Sindhuja Tirumalai Govindarajan, Elizabeth Mamourian; Guray Erus; Ahmed Abdulkadir; Randa Melhem; Jimit Doshi; Raymond Pomponio; Duygu Tosun; Yang An; Aristeidis Sotiras; Daniel S. Marcus; Pamela J. LaMontagne; Mark A. Espeland; Colin L. Masters; Paul Maruff; Lenore J. Launer; Jurgen Fripp; Sterling C. Johnson; John C. Morris; Marilyn S. Albert; R. Nick Bryan; Mohamad Habes; Haochang Shou; David A. Wolk; Ilya M. Nasrallah, and Christos Davatzikos; Machine-learning based MRI neuro-anatomical signatures associated with cardiovascular and metabolic risk factors; Alzheimer’s Imaging Consortium ORAL presentation and Alzheimer’s Association International Conferences POSTER presentation, 2022
Sindhuja T. Govindarajan, Thomas Ren, Peter Hsu, Pallavi Srivastava, Hongyi Duanmu, Haifang Li, Patricia M. Coyle, Lev Bangiyev, Robert G. Peyster, Tim Q. Duong; Convolutional Neural Network for Automated Segmentation of Multiple Sclerosis White Matter Lesions on Multi-parametric MRI; Society for Imaging Informatics in Medicine (VIRTUAL TALK) 2020
Sindhuja T Govindarajan, Ruiqi Pan, M. Andrea Parra, Leigh Charvet, Lauren Krupp,Timothy Duong; Frontoparietal cortical thinning in impaired executive control in young-adult multiple sclerosis; Radiological Society of North America POSTER presentation, 2019
Sindhuja T Govindarajan, Gregory Bodik, Yilin Liu, Leigh Charvet, Lauren Krupp, and Timothy Duong: Functional connectivity correlates of altered intraindividual variability of processing speed in multiple sclerosis patients with young adult onset; International Society of Magnetic Resonance in Medicine POSTER presentation, 2019
Sindhuja T. Govindarajan, M. Andrea Parra, Tao Wang, Kenneth Wengler, Chuan Huang, Xiang He, Leigh Charvet, Lauren Krupp, and Tim Q Duong: Brain structural damage and atrophy correlates of impaired processing speed in pediatric onset multiple sclerosis; Radiological Society of North America POSTER presentation, 2018
Sindhuja T Govindarajan, David J Ouellette, Junghoon Kim, and Tim Q Duong: Regional fractional anisotropy and processing speed in diffuse traumatic brain injury: An exploratory analysis using a linear regression panel model; International Society of Magnetic Resonance in Medicine POSTER presentation, 2018
Sindhuja T. Govindarajan, M. Andrea Parra, Tao Wang, Kenneth Wengler, Chuan Huang, Xiang He, Leigh Charvet, Lauren Krupp, and Tim Q Duong: Diffusivity and the neurocognitive domains of premorbid intelligence and visuospatial memory in Pediatric Multiple Sclerosis; International Society of Magnetic Resonance in Medicine POSTER presentation, 2018
ST Govindarajan, MP Sormani, J Cohen-Adad, C Mainero: Reproducibility of surface-based laminar measures of T2 (star) relaxation decay in the cortex at 7 Tesla MRI. 28th Congress of the European Committee for Treatment and Research in Multiple Sclerosis; POSTER presentation, 10/2012
Sindhuja T Govindarajan, Siddarth Chandrasekharan, Walter O’Dell: Automated Segmentation of Blood Vessels in the Presence of Fibrosis in Volumetric Lung CT Images. Biomedical Engineering Society Annual Meeting; POSTER presentation, 10/2011